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The book gives an introduction to the world of mathematical programming and data analytics and is mainly written for M.Sc. and MBA students at Ghent University, Vlerick Business School and UCL School of Management of University College London. On top of that, the book also contains an overview of research studies and company applications of data-driven modelling technique developed by the Operations Research & Scheduling group, which makes the book potentially relevant for researchers and professionals interested in the new data-driven management approach. The book is free for download via the OR-AS site and will be updated on a regular basis upon requests and comments of the readers.